ABOUT CAFERGOT DISCONTINUED

Keep track of Intently (1)mitotane decreases amounts of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Mitotane is a strong inducer of cytochrome P-4503A4; keep an eye on when coadministered with CYP3A4 substrates for feasible dosage adjustments.Ergotism manifested by powerful arterial vasoconstriction, gene